Feed-forward loops (FFLs), a three-node graph of the form A affects B and C and B affects C, are frequently observed in transcription networks in several organisms including E. coli and S. cerevisiae, suggesting that they perform functions that are important for the functioning of these organisms.
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One of these motifs is the feed-forward loop (FFL). The FFL, a three-gene pattern, is composed of two input transcription factors, one of which regulates the ...
Aug 19, 2022 · Feedforward loops (FFLs) are relatively simple network motifs, made of three interacting genes, that have been found in a large number in E.
This fold-change detection property means that the dynamics of the output (amplitude and duration of the transcription of gene Z) depends only on the relative ...
Network motifs play an important role in the qualitative analysis and quantitative characterization of networks. The feed-forward loop is a semantically ...
Jan 23, 2020 · In a motif described as a feed forward loop (FFL), transcription factor A regulates expression of two targets, B and C (Fig. 1A). B also acts as ...